Seroconversion of acute hepatitis B by antiretroviral therapy in an HIV-1 infected patient
| Journal | Volume 73 - 2010 |
| Issue | Fasc.3 - Case reports |
| Author(s) | Mahoko Ikeda-Kamimura, Masahide Horiba |
| Full article |
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| (1) Division of Respiratory Medicine, National Hospital Organization, Higashi-Saitama Hospital ; (2) Department of Infectious Diseases, Graduate school of Medicine, the University of TokyO. Japan. |
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A 33-year-old man with human immunodeficiency virus type1 (HIV-1) infection was admitted because of acute hepatitis B. His serum alanine aminotransferase level was 1200 IU/mL and CD4 cells count was 268/mm3. Antiretroviral therapy including teno- fovir and emtricitabine, which suppresses both HIV and hepatitis B virus (HBV) replication, was initiated. The liver enzymes decreased dramatically. The viral loads of both HIV-1 and HBV were suppressed below detectable limits. Seroconversion from hepatitis B surface antigen to hepatitis B surface antibody was acquired 19 weeks later. In this case, the initiation of antiretrovi- ral therapy with anti-HBV activity during the acute phase of hepatitis B had a favourable effect on HBV serostatus. (Acta gas- troenterol. belg., 2010, 73, 389-391). |
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© Acta Gastro-Enterologica Belgica. PMID 21086945 |
